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Archive for October, 2010

The Near Eastern Origin of Cat Domestication in Fredcobio

Posted by Jim H on October 31, 2010

I am always amazed at the breadth and depth of scientific research going down in our own back yard. I bet you didn’t know that this 2007 paper in Science was partially done in Frederick: The Near Eastern Origin of Cat Domestication

A few weeks back I went to Olive’s, on a whim, and ended up chatting with this cat Carlos who works at the Laboratory of Genomic Diversity at NCI over a martini or two.  Fascinating stuff.   The research shows that wildcats (Felis silvestris) were initially domesticated in the Near East, probably coincident with agricultural village development in the Fertile Crescent.  Interestingly, cats differ from other domesticated animals in that they seem to provide no real benefit to humans aside from catching rodents in the early grain stores & companionship.

The Science text is a very detailed technical account and is followed up with a more elaborate, “scientifically toned down” article in the June 2009 edition of  Scientific American.

Some conclusions of this article

Unlike other domesticated creatures, the house cat contributes little to human survival.  Researchers have therefore wondered how and why cats came to live among people.

Experts traditionally thought that the Egyptians were the first to domesticate the cat, some 3,600 years ago. But recent genetic and archaeological discoveries indicate that cat domestication began in the Fertile Crescent, perhaps around 10,000 years ago, when agriculture was getting under way.

The findings suggest that cats started making themselves at home around people to take advantage of the mice and food scraps found in their settlements.

In an article published in PNAS in 2009, the authors delve into the differences between Natural vs. Artificial Selection.  Interesting stuff:

We perceive today, as did Darwin, that natural selection is the environmentally driven mechanistic process by which more advantageous traits are, on the whole, passed on to succeeding generations more often than less advantageous traits because of differential reproduction of the individuals possessing them. Sexual selection is a natural process of intraspecific competition for mating rights. Artificial selection, generally the motive force behind domestication, is often equated with selective breeding. This often amounts to prezygotic selection (where mates are chosen by humans) versus postzygotic selection (where the most fit progeny reproduce differentially) as in natural selection. Although natural selection plays a considerable role in the evolution of many traits (e.g., disease resistance) during the animal domestication process, sexual selection is effectively trumped by the human-imposed arrangements of matings and often by the human desire for particular secondary sexual characters. Artificial selection is a conscious, if unintentional, process, and therefore is generally considered to be effected only by humans.

This is exactly the kind of research we’re doing at Ft Detrick that I think would be brilliant to get out to people by a yet to be established mechanism. I wonder if The various agency “partners” at Ft Detrick even track this stuff?

Posted in Academia, General Biology, Genetics, Government Funded research, Molecular Biology, News | Leave a Comment »

Last Minute Update

Posted by Jim H on October 13, 2010

Just a heads up for anyone traveling through downtown to Biobeers tonight at 4:30 PM.   Gas House Pike/Church Street extension is CLOSED at the new Monocacy Blvd/East St By-pass construction site, so you’ll have to come up East St, N Market or 15 to Rt 26 and down Monocacy Blvd tonight.  Don’t get lost.  Directions are HERE: http://is.gd/fKmkQ (assuming you haven’t seen these eight times already).

Also found out this morning that Stem Cell guru (my words, not his) Dr Mahendra Rao from Life Tech will be giving a presentation in addition to Dr Jack Collins from NCI-Frederick, so everyone must be on their best behavior.

I will also announce that yours truely is one of the first 1000 humans on the planet to have their genome fully sequenced.  Who would’ve thought old white guys fit the demographic they’re looking for?  I am in awe and honored to be selected.

I hope you can join us this evening.  I am looking forward to it.

 

Posted in Uncategorized | Leave a Comment »

Do You Need Direction?

Posted by Jim H on October 12, 2010

Noelle, our hostess with Matan, put together this neat little flier for Biobeers tomorrow

Jack R. Collins, Director, Advanced Biomedical Computing Center SAIC-Frederick, National Cancer Institute at Frederick will address the troops. I hope he tells us about long homopurine-homopyrimidine sequences in the pseudoautosomal region or about the abundance and length of simple repeats in vertebrate genomes. That would be awesome.

The response has been great, but still plenty of room for more.  Please come out and join us!

Posted in Uncategorized | Leave a Comment »

Fredcobio was kinda almost in Nature

Posted by Jim H on October 6, 2010

We were this close to having a mention in Nature today. OK, since the company these guys are a part of is based in FITCI in Frederick, I guess we were in Nature today. But you should read it.

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More on BioBeers in October

Posted by Jim H on October 4, 2010

In case you haven’t heard, the next BioBeers was set last week for Wednesday October 13th, starting at 4:30 PM.  You can RSVP through the LinkedIn event HERE , leave a comment on this post or just send me an e-mail.  Directions to the Riverside Five building (the new white one behind the massive Wells Fargo building), Third Floor are here: http://is.gd/fKmkQ

Event sponsors are Lifetech and the Matan group.  Beer by Barley & Hops and some sandwiches and such from aka Frisco’s.  I hope you can make it!

Posted in BioBeer | Leave a Comment »

 
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